The session will be covering different methods of sequencing with respect to clinical implications (genome, exome, transcriptome, panel) and will provide an outlook especially focussing on liquid biopsy, tumor mutational burden and neoantigen prediction.

Expert: Dr. Dr. Saskia Biskup

Location: Lehr- und Lerngebäude 1.202/203

The session will be divided into 3 sections: 1. Introducing the scientific background (about 30 minutes) 2. Students will be divided into groups and each group will be given some topics to dicuss (about 30 minutes) 3. Discussion about the state of art of the field, current questions and technical challanged (about 60 minutes).

Expert: Dr. Uris Ros or Prof. Dr. Ana J. García-Sáez

Location: IFIB, first floor, Garcia-Saez lab, room 209

Suggested previous knowledge: Basics of cell death

This workshop is divided into 2 parts:

1) Lecture on T-cell assays with special focus on their application for monitoring clinical studies: approx 60 min
2) visit of the lab (Elispot and flow cytometer) and open discussion on the techniques: approx 60 min

Expert: PD Dr. Cécile Gouttefangeas

Location: Verfügungsgebaude, Auf der Morgenstelle 15, Seminar Raum 1.034 (lecture) and Abt Immunologie, Raum 3.065 (lab)

Suggested previous knowledge: Basics of immunology

A medical scenario will be critically evaluated and analyzed as a group. This interactive discussion will highlight the importance of active and independent learning, and will encourage attendees to develop their communication skills, critical thinking abilities, and leadership.

Expert: Dr. Tamia Lapointe 

Location: Crona, Seminarraum 224

Suggested previous knowledge: Basics of human physiology

In this workshop, we will examine how molecular analyses have been crucial for deciphering the function and heterogeneity of microglial cells (brain macrophages). We will also study how molecular approaches can be used to manipulate specific cell types and such approaches can be used for evaluating new treatment options for brain diseases.

Expert: Dr. Jonas Neher

Location: Lehr- und Lerngebäude 1.206

Suggested previous knowledge: Basics of neuroscience and immunology

We will both give an overview about the topic and then discuss with the group what they think still has to be done in basic science and in clinical trials.

Experts: Prof. Dr. Birgit Schittek and Dr. Tobias Sinnberg

Location: Lehr- und Lerngebäude 1.205

Suggested previous knowledge: Basics of oncology

How are human disease genes discovered? Students will first be introduced to the variability of the human genome, learn how to interpret genetic variation and then learn the strategies how disease genes are discovered and validated. To exemplify the principles we will work with 'real life' whole exome and whole genome sequencing data and use key genomic databases.

Expert: PD Dr. Rebecca Schüle

Location: Lehr- und Lerngebäude 2.202

Suggested previous knowledge: Basics of human genetics

Introduction in the topic and main methodological aspects of the CRISPR/Cas9 mediated gene editing and iPSC generation will be provided. After that, the implementation of the discussed methods in the (1) disease modelling or (2) correction of disease-casing mutations will be developed together with the partcipants in small groups.

Expert: Prof. Dr. Julia Skokowa

Location: probably: Crona 221

Suggested previous knowledge: Basics of cell and molecular biology and genetics

Hand on workshop with a classic model organism (2 and 5 days old chicken embryo). In this Workshop you will learn the basics of the anatomy of higher vertebrates. First, you will see a demonstration of a 3-days-old chicken embryo via video-microscopy and get explained the general anatomy of embryos. Then, you have the chance to prepare your own chicken embryo on pairs of two or three students. It is your chance to investigate chicken embryos in ovo and in vitro.

Expert: PD Dr. Andrea Wizenmann

Location: Felsenbeinlabor, HNO

The session will be a mix of theoretical presentations and practical hands-on demonstrations. We will discuss basics in light and electron microscipy, and advanced methods of optical sectioning and superresolution. The practical part will include working on confocal microscopes (multichannel imaging and image stacks) and optional a demonstration of an electron microscope.

Expert: Dr. Andreas Mack

Location: Anatomie, Österbergstr. 3 Seminar/Mikroskopräume

Get acquainted with a zebrafish facility and the utility of zebrafish for basic and translational research. Observe and draw wildtype and mutant embryos at various stages using stereomicroscopes and observe transgenic reporter embryos using a fluorescence microscope.

Expert: Dr. Patrick Müller

Location: FML, Max-Planck-Ring 9

This workshop will give an overview on the discovery of the major histocompatibility complex (MHC). It will introduce and discuss the work that led to Nobel prizes in 1980 and 1996. The workshop will be divided into three parts: After an introduction into the topic, the participants will form four groups and deal with the scientific work on MHC. In the final presentation each group will present their findings. The participants will be introoduced into the immunological work, which among other things, provided far-reaching insights for organ transplantation.

Expert: Prof. Dr. Oliver Planz

Location: Lehr- und Lerngebäude 2.201

Suggested previous knowledge: Basics of immunology

Other: Bring your own Laptop or Tablet!